Understanding Exemestane
Exemestane is a medication commonly used to treat breast cancer in postmenopausal women. It is classified as an aromatase inhibitor, which works by decreasing the amount of estrogen produced in the body. This helps to slow or stop the growth of hormone receptor-positive breast cancer cells. To learn more about Exemestane indications for use, visit Exemestane order in store.
Indications for Use
Exemestane is indicated for the following scenarios:
- Adjuvant Treatment of Early-Stage Breast Cancer: Exemestane is used as an adjuvant therapy for postmenopausal women who have early-stage, hormone receptor-positive breast cancer, following two to three years of tamoxifen therapy.
- Advanced Breast Cancer: It is indicated for the treatment of advanced breast cancer in postmenopausal women whose disease has progressed following antiestrogen therapy.
- Prevention of Recurrence: Exemestane can be used to reduce the risk of recurrence in patients who have previously experienced an estrogen receptor-positive breast cancer.
Mechanism of Action
As an aromatase inhibitor, Exemestane works by irreversibly binding to the aromatase enzyme, which is responsible for converting androgens into estrogens in postmenopausal women. By inhibiting this enzyme, Exemestane effectively lowers estrogen levels in the body, thereby reducing the stimulus for the growth of hormone-dependent cancers.
Conclusion
Exemestane plays a critical role in the management of hormone receptor-positive breast cancer in postmenopausal women. Its use in both adjuvant and advanced settings reflects its importance in improving patient outcomes in breast cancer treatment.